Timothy W Secomb Selected Research

green 5

12/2013	Design of optimized hypoxia-activated prodrugs using pharmacokinetic/pharmacodynamic modeling.
1/2013	The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104.
11/2004	Green's function methods for analysis of oxygen delivery to tissue by microvascular networks.

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Timothy W Secomb Research Topics

Disease

18	Neoplasms (Cancer) 03/2022 - 05/2002
10	Hypoxia (Hypoxemia) 03/2022 - 08/2006
2	Hyperthermia 03/2022 - 03/2004
2	Hypertension (High Blood Pressure) 03/2016 - 01/2015
2	Neoplasm Metastasis (Metastasis) 09/2004 - 03/2004
1	Sarcoma (Soft Tissue Sarcoma) 03/2022
1	Pathologic Complete Response 03/2022
1	Critical Illness (Critically Ill) 01/2021
1	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 04/2020
1	Alzheimer Disease (Alzheimer's Disease) 01/2018
1	Hyperemia 01/2017
1	Atherosclerosis 03/2016
1	Vascular Remodeling 01/2015
1	Vascular Diseases (Vascular Disease) 01/2014
1	Colitis 05/2013
1	Colonic Neoplasms (Colon Cancer) 08/2006
1	Fibrosarcoma 09/2004
1	Carcinoma (Carcinomatosis) 08/2003

Drug/Important Bio-Agent (IBA)

14	Oxygen (Dioxygen)IBA 01/2021 - 05/2002
5	Pharmaceutical PreparationsIBA 03/2022 - 03/2004
3	Angiotensin IIIBA 01/2015 - 01/2014
3	green 5IBA 12/2013 - 11/2004
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 05/2002
2	Biological ProductsIBA 03/2016 - 05/2009
2	Tirapazamine (SR 4233)IBA 12/2013 - 08/2006
2	ProdrugsIBA 12/2013 - 01/2013
2	Glucose (Dextrose)FDA LinkGeneric 06/2004 - 08/2003
2	Cisplatin (Platino)FDA LinkGeneric 03/2004 - 03/2003
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 04/2020
1	Immunoconjugates (Immunoconjugate)IBA 12/2019
1	AntigensIBA 12/2019
1	AminopropionitrileIBA 01/2015
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2015
1	TH 302IBA 12/2013
1	CEN-209IBA 12/2013
1	OxidesIBA 12/2013
1	Nitro CompoundsIBA 12/2013
1	AcidsIBA 05/2013
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 05/2013
1	Dextrans (Dextran)FDA Link 05/2013
1	PR-104AIBA 01/2013
1	Oxidoreductases (Dehydrogenase)IBA 01/2013
1	Phosphates (Orthophosphate)IBA 01/2013
1	PR-104IBA 01/2013
1	EstersIBA 01/2013
1	ConnexinsIBA 01/2011
1	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2005
1	pimonidazoleIBA 09/2004
1	Pentobarbital (Nembutal)FDA Link 09/2004
1	SugarsIBA 08/2003
1	Mannitol (Osmitrol)FDA LinkGeneric 08/2003
1	GasesIBA 05/2002

Therapy/Procedure

5	Radiotherapy 03/2022 - 05/2002
3	Therapeutics 01/2019 - 03/2003
2	Drug Therapy (Chemotherapy) 03/2022 - 01/2018
2	Microelectrodes 02/2006 - 09/2004
1	Immunotherapy 01/2019
1	Aftercare (After-Treatment) 08/2006